The largest city on the Rhine, its commercial importance was already established as long ago as the Middle Ages. In the time of the Roman Empire, Cologne was the most important trading and manufacturing centre north of the Alps.
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| A-Rosa River Cruises | ||||||||||||
| AMA Waterways | ||||||||||||
| Avalon Waterways | ||||||||||||
| CroisiEurope | ||||||||||||
| Emerald Cruises | ||||||||||||
| Scenic Cruises | ||||||||||||
| Tauck Cruise | ||||||||||||
| Uniworld Boutique River Cruise Collection | ||||||||||||
| Viking River Cruises |